Department of Anesthesiology and Intensive Care First Faculty of Medicine Charles University in Prague and General University Hospital in Prague
ACUTE PAIN AND POSTOPERATIVE OXIDATIVE STRESS
The influence of premedication on the oxidative stress and on the releasing of free radicals after the surgical interventions.
The objective evaluation, acute postoperative stress, surgical intervention by herniotomy, VAS (visual analogue scale), objective evaluation of pain, MC-Gill University questionnarie, changes of spectrum of lipids, sacharides and proteins, measurement of free radicals changes (TBARS, MDA, SOD, GPX, total antioxidant capacity), direct measurement of free radicals by EPR method (Elektronparamagnetic resonancy).
Contact: MUDr.Jitka Fricová (jitka.fricova@vfn.cz)
Grant: Research concept of
Publication:
The evaluation of nociceptive intensity by using free radicals, direct measurement by EPR method in the tail of anaesthetized rats.
Rokyta R. , Stopka P., Kafuňková E., Křížová J., Fricová J., Holecek V.
Neuroendocrinology Letters 2008; 29(6):1007-1014
The effect of laparotomy on hydroxyl radicals, singlet oxygen and antioxidants measured by EPR method in the tails of rats
Fricova J, Stopka P.,Krizova J.,Yamamotova A., Rokyta R
Neuroendocrinology Letters 2009; 30(3):152-156
Posters:
Direct Measurement Of Free Radicals In The Tail Of Anaesthized Rats By Using The EPR Method
Fricová J.,Stopka P., Křížová E.,Yamamotová A. , Rokyta R.,: European Journal of pain, 5th congress of the European Federation of IASP Chapters(EFIC), Istanbul, Turkey, 2006
Direct Measurement of Free Radicals Using The EPR Metod For The Evaluation of Nociception Fricova J., Stopka P.,Křížová E.,Holeček V., Rokyta R.: Book of abstracts of 3rd International Forum on pain Medicine, Montreal, Canada, 2007
Free Radicals Changes After Surgical Interventions With Different Types Of Premedications
Fricová J.,Vejražka M.,Stopka P., Křížová E., Rokyta R.,: Book of abstracts of the 12th World Congress on Pain Glasgow, Scotland, 2008
Lectures:
Role Of Antioxidants On Elevated Hydroxyl Radicals And Singlet Oxygen Measured By Epr Method In The Tail Of Living Rats Fricova J, Stopka P, Krizova J, Yamamotova A, RokytaR: Book of abstract 6th Pain congress on Pain EFIC IASP Lisabon, Portugal 2009
Kontakt
Klinika anesteziologie, resuscitace a intenzivní medicíny 1.LF UK
Všeobecná fakultní nemocnice
U Nemocnice 2
128 08 Praha 2
tel. 224 962 243
fax 224 962 118
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